Actinic Keratosis Features


  • Actinic keratosis presents with atypical thickening of the epidermis
  • Thickening of the epidermis at the lesion edges is usually focused to the Stratum Corneum layer


  • They can sometimes present with an area of underlying lymphocytic infiltrate from inflammation (*)


  • Actinic keratosis can sometimes be identified by the meshing of the Stratum Corneum and Spinosum layers at their interface opposed to the distinct boundary that is encountered in other squamous derived lesions.
  • Attributed to the loss of the granular layer

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