Dermal-Epidermal Junction

• Interface of the epidermis and the papillary dermis

• Identified by dramatic change in contrast or in instances a fine hyporeflective line at the interface

• DEJ appearance involves Stratum Basale and the Rete pegs

• The hyporeflective line at the interface differs in prominence between skin and may be entirely absent in some regions

• In all healthy skin the change in contrast between epidermis and papillary dermis is always evident

• Absence, prominence and distortion of the DEJ can be an indication of pathology